N-[BIS(METHYLTHIO)METHYLENE]AMINO ESTERS (BMMA) - NOVEL REAGENTS FOR ANNELATION OF PYRIMIDINE MOIETIES

被引：40

作者：

SAUTER, F ^{[1
]}

FROHLICH, J ^{[1
]}

BLASL, K ^{[1
]}

GEWALD, K ^{[1
]}

机构：

[1] TECH UNIV DRESDEN,INST ORGAN CHEM,O-1217 DRESDEN,GERMANY

来源：

HETEROCYCLES | 1995年 / 40卷 / 02期

关键词：

D O I：

10.3987/COM-94-S86

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

New reagents for heterocyclic annelations containing a N-[bis(methylthio)methylene]amino moiety (=BMMA) were developed and studied regarding their scope and limitations: one-pot reaction with (hetero)aromatic ortho-aminocarbonyl-type model compounds (''carbonyl'' = COOEt, COMe and CN) to a series of new benzo- or thieno-condensed pyrimidines, pyrrolo[1,2-c]pyrimidines, imidazo[1,2-c]pyrimidines and 1,2,4-triazolo[1,5-c]pyrimidines, depending on the reagent used [(MeS)(2)C=N-R with R = CH2-COOEt, CH(2)CH(2)COOEt, NH-COOEt].

引用

页码：851 / 866

页数：16

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