RESISTANCE OF CANDIDA-ALBICANS BIOFILMS TO ANTIFUNGAL AGENTS IN-VITRO

被引：313
|
作者：
HAWSER, SP [1 ]
DOUGLAS, LJ [1 ]
机构：
[1] UNIV GLASGOW,INST BIOMED & LIFE SCI,DIV MOLEC & CELLULAR BIOL,MICROBIOL LAB,GLASGOW G12 8QQ,LANARK,SCOTLAND
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1995年 / 39卷 / 09期
关键词：
D O I：
10.1128/AAC.39.9.2128
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
Biofilms formed by Candida albicans on small discs of catheter material were resistant to the action of five clinically important antifungal agents as determined by [H-3]leucine incorporation and tetrazolium reduction assays. Fluconazole showed the greatest activity, and amphotericin B showed the least activity against biofilm cells. These findings were confirmed by scanning electron microscopy of the biofilms.
引用
收藏
页码：2128 / 2131
页数：4
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