OSSEOINTEGRATION OF MACROPOROUS CALCIUM-PHOSPHATE CERAMICS HAVING A DIFFERENT CHEMICAL-COMPOSITION

被引:151
作者
FRAYSSINET, P [1 ]
TROUILLET, JL [1 ]
ROUQUET, N [1 ]
AZIMUS, E [1 ]
AUTEFAGE, A [1 ]
机构
[1] ECOLE NATL VET TOULOUSE,F-31076 TOULOUSE,FRANCE
关键词
CERAMICS; HYDROXYAPATITE; TRICALCIUM PHOSPHATE; OSSEOINTEGRATION;
D O I
10.1016/0142-9612(93)90144-Q
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Calcium phosphate macroporous ceramics are biocompatible for bone surgery. Their osseointegration is, however, sometimes very poor. To measure the effect of the calcium phosphate content of the ceramic on its osseointegration, macroporous ceramics, differing in their chemical composition, were implanted into sheep femurs. The ceramics were composed of different percentages of hydroxyapatite (HA) and beta-tricalcium phosphate (beta-TCP). All other characteristics were the same. Results were assessed histologically with image analysis and showed significant differences in the amount of bone formed at the contact of the different ceramics. Ceramics containing beta-TCP induced better osseointegration than pure HA ceramics.
引用
收藏
页码:423 / 429
页数:7
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