Daptomycin for a complicated urinary tract infection with vancomycin-resistant Enterococcus faecium in a renal transplant recipient

被引：4

作者：

Eden, Gabriele ^{[1
]}

Burkhardt, Olaf ^{[2
]}

Clajus, Christian ^{[1
]}

Kielstein, Jan T. ^{[1
]}

机构：

[1] Med Sch Hannover, Dept Nephrol & Hypertens, Hannover, Germany

[2] Med Sch Hannover, Dept Pulm Med, Hannover, Germany

来源：

CLINICAL KIDNEY JOURNAL | 2012年 / 5卷 / 04期

关键词：

renal transplant recipient; urinary tract infection; vancomycin-resistant entorococci;

D O I：

10.1093/ckj/sfs076

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

There is an increasing prevalence of urinary tract infection (UTI) caused by multiresistant gram-negative enteric bacilli such as extended-spectrum beta-lactamase as well as Gram-positive enterococci whose vancomycin-resistance can be as high as 25%. We report on a 68-year-old Caucasian female with a UTI caused by a vancomycin-resistant Enterococcus faecium, only tested to be susceptible to gentamycin, linezolid and daptomycin. Within a day after administration of the bactericidal daptomycin clinical and laboratory signs of infection regressed and graft function recovered. Our case suggests that daptomycin might be an effective alternative for UTI caused by vancomycin-resistant enterococci.

引用

页码：350 / 355

页数：6