THE INFLUENCE OF MIDAZOLAM ON THE PLASMA-CONCENTRATIONS OF BUPIVACAINE AND LIDOCAINE AFTER CAUDAL INJECTION OF A MIXTURE OF THE LOCAL-ANESTHETICS IN CHILDREN

被引：12

作者：

GIAUFRE, E

BRUGUEROLLE, B

MORRISONLACOMBE, G

ROUSSETROUVIERE, B

机构：

[1] ST JOSEPH FDN HOSP,DR RANQUE LAB,F-13008 MARSEILLE,FRANCE

[2] FAC MED MARSEILLE,MED & CLIN PHARMACOL LAB,F-13385 MARSEILLE 5,FRANCE

来源：

ACTA ANAESTHESIOLOGICA SCANDINAVICA | 1990年 / 34卷 / 01期

关键词：

Bupivacaine; caudal anesthesia; lidocaine; local anesthetics; midazolam;

D O I：

10.1111/j.1399-6576.1990.tb03039.x

中图分类号：

R614 [麻醉学];

学科分类号：

100217 ;

摘要：

Twenty children undergoing surgery received a caudal block using 1 ml per kg of a mixture of 50% lidocaine (1%) and 50% bupivacaine (0.25%). They were randomly allocated to two groups, one of which received midazolam 0.4 mg/kg rectally as premedication. Midazolam administration resulted in a significantly lower AUC value for lidocaine but did not influence the plasma concentrations of bupivacaine. © 1990 Acta Anaesthesiologica Scandinavica Fonden

引用

页码：44 / 46

页数：3

共 8 条

[1]

CAMBOULIVES J, 1986, Annales Francaises d'Anesthesie et de Reanimation, V5, P115, DOI 10.1016/S0750-7658(86)80091-0

[2] BUPIVACAINE IN CHILDREN - PHARMACOKINETICS FOLLOWING CAUDAL ANESTHESIA [J].