NEW GENERAL-SYNTHESIS OF ORGANOPHOSPHORUS P-F COMPOUNDS VIA REACTION OF AZOLIDES OF PHOSPHORUS-ACIDS WITH ACYL FLUORIDES - NOVEL ROUTE TO 2-DEOXYNUCLEOSIDYL PHOSPHOROFLUORIDATES AND PHOSPHORODIFLUORIDATES

被引：21

作者：

DABKOWSKI, W

MICHALSKI, J

WASIAK, J

CRAMER, F

机构：

[1] POLISH ACAD SCI,CTR MOLEC & MACROMOLEC STUDIES,PL-90363 LODZ,POLAND

[2] MAX PLANCK INST EXPTL MED,W-3400 GOTTINGEN,GERMANY

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 07期

关键词：

D O I：

10.1039/p19940000817

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Tetra- and tri-coordinate P-N-imidazole derivatives and their structural analogues react smoothly with acyl fluorides to give the corresponding P-F compounds in almost quantitative yield. This method has been successfully applied to produce 2-deoxynucleosidyl phosphorofluoridates and phosphorodifluoridates.

引用

页码：817 / 820

页数：4

共 30 条

[1]

BOTER HL, 1966, RECL TRAV CHIM PAY-B, V85, P21

[2] FLUORINATION OF TRIMETHYLSILYL PHOSPHITES AND THEIR STRUCTURAL ANALOGS BY SULFURYL CHLORIDE FLUORIDE - A FACILE PREPARATION OF PHOSPHOROFLUORIDATES AND RELATED-COMPOUNDS [J].