SERUM-CATALYZED HYDROLYSIS OF METRONIDAZOLE AMINO-ACID ESTERS

被引：22
作者：
CHO, MJ
HAYNES, LC
机构：
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 1985年 / 74卷 / 08期
关键词：
D O I：
10.1002/jps.2600740817
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
引用
收藏
页码：883 / 885
页数：3
相关论文
共 16 条
[1]   SURFACE-TENSION OF AMINO-ACID SOLUTIONS - HYDROPHOBICITY SCALE OF AMINO-ACID RESIDUES [J].
BULL, HB ;
BREESE, K .
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1974, 161 (02) :665-670
[2]   PRODRUGS AS DRUG DELIVERY SYSTEMS .26. PREPARATION AND ENZYMATIC-HYDROLYSIS OF VARIOUS WATER-SOLUBLE AMINO-ACID ESTERS OF METRONIDAZOLE [J].
BUNDGAARD, H ;
LARSEN, C ;
THORBEK, P .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1984, 18 (1-2) :67-77
[3]   PRODRUGS AS DRUG DELIVERY SYSTEMS .27. CHEMICAL-STABILITY AND BIOAVAILABILITY OF A WATER-SOLUBLE PRODRUG OF METRONIDAZOLE FOR PARENTERAL ADMINISTRATION [J].
BUNDGAARD, H ;
LARSEN, C ;
ARNOLD, E .
INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1984, 18 (1-2) :79-87
[4]  
CHARTON M, 1977, DESIGN BIOPHARMACEUT, P228
[5]  
CHO MJ, 1982, J PHARM SCI, V71, P410, DOI 10.1002/jps.2600710409
[6]   CHEMICOBIOLOGICAL INTERACTIONS AND USE OF PARTITION-COEFFICIENTS IN THEIR CORRELATION [J].
DUNN, WJ ;
HANSCH, C .
CHEMICO-BIOLOGICAL INTERACTIONS, 1974, 9 (02) :75-95
[7]  
Hansch C, 1979, SUBSTITUENT CONSTANT
[8]  
MOROZOWICH W, 1977, DESIGN BIOPHARMACEUT, P344
[9]   A SIMPLEX-METHOD FOR FUNCTION MINIMIZATION [J].
NELDER, JA ;
MEAD, R .
COMPUTER JOURNAL, 1965, 7 (04) :308-313
[10]   PRODRUG DESIGN [J].
NOTARI, RE .
PHARMACOLOGY & THERAPEUTICS, 1981, 14 (01) :25-53
12