TISSUE CONCENTRATIONS OF WATER-SOLUBLE VITAMINS IN NORMAL AND DIABETIC RATS

被引：0

作者：

REDDI, AS ^{[1
]}

JYOTHIRMAYI, GN ^{[1
]}

DEANGELIS, B ^{[1
]}

FRANK, O ^{[1
]}

BAKER, H ^{[1
]}

机构：

[1] UMDNJ,NEW JERSEY MED SCH,DEPT PREVENT & COMMUNITY HLTH,NEWARK,NJ 07103

来源：

INTERNATIONAL JOURNAL FOR VITAMIN AND NUTRITION RESEARCH | 1993年 / 63卷 / 02期

关键词：

STREPTOZOTOCIN DIABETES; RATS; TISSUE VITAMINS;

D O I：

暂无

中图分类号：

R15 [营养卫生、食品卫生]; TS201 [基础科学];

学科分类号：

100403 ;

摘要：

Changes in circulating and tissue concentrations of several vitamins have been reported in diabetic animals and human subjects. In this study, the effect of short-term (2 weeks) streptozotocin diabetes on folate, B6, B12, thiamin, nicotinate, pantothenate, riboflavin and biotin in liver kidney, pancreas, heart, brain and skeletal muscle of rats was investigated. The tissue distribution of vitamins varied widely in normal rats. Diabetes significantly lowered folate in kidney, heart, brain, and muscle; B6 in brain; B12 in heart; thiamin in liver and heart; nicotinate in liver kidney, heart and brain; pantothenate in all tissues; riboflavin in liver kidney, heart, and muscle. These results indicate that experimental diabetes causes a depression of several water-soluble vitamins in various tissues of rats.

引用

页码：140 / 144

页数：5

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