1-ACYL-2-ALKYL-3,4-EPOXY-1,2,3,4-TETRAHYDROQUINOLINES - SYNTHESIS AND REACTIONS WITH N-NUCLEOPHILES

被引：11
作者：
KRATZEL, M
HIESSBOCK, R
机构：
[1] Institut für Pharmazeutische Chemie der Universität Wien, A-1090 Wien
来源：
HETEROCYCLES | 1995年 / 41卷 / 05期
关键词：
D O I：
10.3987/COM-94-6677
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Epoxide opening of the title compounds (6) with primary or secondary amines using lithium perchlorate as catalyst gave 1,2,3,4-tetrahydroquinolines with stereochemically well defined substitution pattern in the piperidine moiety (7,8). By-products (9,10), formed by acyl migration, were observed.
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收藏
页码：897 / 909
页数：13
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