A NONCATALYZED RING-OPENING AMINOLYSIS REACTION OF SESQUITERPENE LACTONES

被引：15

作者：

BLAY, G ^{[1
]}

CARDONA, L ^{[1
]}

GARCIA, B ^{[1
]}

GARCIA, CL ^{[1
]}

PEDRO, JR ^{[1
]}

机构：

[1] UNIV VALENCIA,FAC QUIM,DEPT QUIM ORGAN,E-46100 BURJASSOT,SPAIN

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 06期

关键词：

D O I：

10.1016/S0040-4039(00)76003-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Santonin (1) and other sesquiterpene lactones (6-10) react cleanly with pyrrolidine at room temperature to afford gamma-hydroxyalkylamides, which by elimination with mesyl chloride in pyridine-benzene at 80 degrees C give unsaturated alkylamides.

引用

页码：931 / 934

页数：4

共 9 条

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