ON SYNTHESIS OF RNA IN LYMPHOCYTES STIMULATED BY PHYTOHEMAGGLUTININ .1. INDUCTION OF URIDINE-KINASE AND CONVERSION OF URIDINE TO UTP

被引：72

作者：

HAUSEN, P

STEIN, H

机构：

[1] Max-Planck-Institut für Biologie, Abteilung Beermann, Tübingen, 7400

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1968年 / 4卷 / 03期

关键词：

D O I：

10.1111/j.1432-1033.1968.tb00226.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Conversion of uridine to UTP is enhanced in lymphocytes under the influence of phytohemagglutinin concomitant with the induction of uridine kinase. The uridine kinase activity in the induced cells decreases if the cells are treated with antibodies against phytohemagglutinin. The phosphorylation of uridine may be the limiting step in the incorporation of uridine into RNA. Uridine incorporation can thus not be taken as a direct measure of RNA synthesis. Copyright © 1968, Wiley Blackwell. All rights reserved

引用

页码：401 / &

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