CHROMOSOMAL LOCALIZATION OF MOUSE AND HUMAN NEUROTENSIN RECEPTOR GENES

被引：11
作者：
LAURENT, P
CLERC, P
MATTEI, MG
FORGEZ, P
DUMONT, X
FERRARA, P
CAPUT, D
ROSTENE, W
机构：
[1] SANOFI ELF BIORECH, UNITE BIOL MOLEC GENE, F-31676 LABEGE, FRANCE
[2] HOP ST ANTOINE, INSERM, U339, F-75012 PARIS, FRANCE
[3] HOP ENFANTS LA TIMONE, INSERM, U242, F-13385 MARSEILLE, FRANCE
[4] HARVARD UNIV, SCH MED, DEPT CELLULAR & MOLEC PHYSIOL, BOSTON, MA 02115 USA
来源：
MAMMALIAN GENOME | 1994年 / 5卷 / 05期
关键词：
D O I：
10.1007/BF00389545
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Neurotensin is a tridecapeptide that plays several neurotransmitter or neuromodulatory roles both in the central nervous system and in the periphery. These actions are mediated by a high-affinity receptor (Ntsr). Both rat and human cDNAs encoding high-affinity receptors have been recently cloned. The availability of Ntsr probes allowed us to localize the corresponding genes on the mouse and human chromosomes. The present data demonstrate that the Ntsr gene is assigned to the H region of the mouse Chromosome (Chr) 2 and to the long arm of the human Chr 20.
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页码：303 / 306
页数：4
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