REACTIVITY OF ANTIERYTHROCYTE ANTIBODY-INDUCED BY BABESIA-GIBSONI INFECTION AGAINST AGED ERYTHROCYTES

被引：17
作者：
MORITA, T
SAEKI, H
IMAI, S
ISHII, T
机构：
[1] Department of Parasitology, Nippon Veterinary and Animal Science University, Musashino-shi, Tokyo, 180
来源：
VETERINARY PARASITOLOGY | 1995年 / 58卷 / 04期
关键词：
BABESIA GIBSONI; DOG; ANEMIA; PATHOLOGY-PROTOZOA;
D O I：
10.1016/0304-4017(94)00726-S
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
Effects of ageing treatment of erythrocytes to binding activity of the anti-erythrocyte antibody(s) in the serum of dogs infected artificially with Babesia gibsoni were examined by enzyme-linked immunosorbent assay (ELISA) using fixed cell antigen. When erythrocytes made senescent by two artificial ageing treatments, one of which was storing erythrocytes at 37 degrees C in medium for some days and the other was oxidation of erythrocytes with phenylhydrazine, reactivity of anti-erythrocyte antibody(s) in the infected serum to both types of treated erythrocytes was increased. These results suggest that such antibody(s) could play a role as one of the causes of anemia in canine babesiosis.
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页码：291 / 299
页数：9
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