DIRECT INVIVO EVALUATION OF PULMONARY ARTERIAL PATHOLOGY IN CHRONIC CONGESTIVE-HEART-FAILURE WITH CATHETER-BASED INTRAVASCULAR ULTRASOUND IMAGING

被引：21

作者：

PORTER, TR

TAYLOR, DO

FIELDS, J

CYCAN, A

AKOSAH, K

MOHANTY, PK

PANDIAN, NG

机构：

[1] VIRGINIA COMMONWEALTH UNIV,MED COLL VIRGINIA,MCGUIRE VET AFFAIRS MED CTR,RICHMOND,VA 23298

[2] TUFTS UNIV,SCH MED,BOSTON,MA 02111

来源：

AMERICAN JOURNAL OF CARDIOLOGY | 1993年 / 71卷 / 08期

关键词：

D O I：

10.1016/0002-9149(93)91024-C

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Patients with chronic congestive heart failure (CHF) frequently develop secondary pulmonary hypertension. This development is a poor prognostic indicator.1 In addition, secondary pulmonary hypertension that does not improve in response to vasodilators identifies a group of patients who will have a poor outcome after orthotopic heart transplantation.2,3 The structural abnormalities of the pulmonary artery that occur in CHF have been described in autopsy specimens,4 and human studies have demonstrated indirectly that there are alterations in pulmonary vascular impedance and stiffness.5,6 Intravascular ultrasound using high-frequency catheter-based imaging has been performed to quantify pulmonary artery area and diameter in humans.7 It also has been validated as a method of detecting plaque in both elastic and muscular arteries.8 We hypothesized that intravascular ultrasound could be used to characterize the changes in pulmonary vascular morphology and elasticity in CHF. © 1993.

引用

页码：754 / 757

页数：4

共 14 条

[1]

BURKE AP, 1991, MODERN PATHOL, V4, P269

[2]

BUSSIERES LM, 1990, J HEART TRANSPLANT, V9, P124

[3] INTRAVASCULAR ULTRASONOGRAPHY VERSUS DIGITAL SUBTRACTION ANGIOGRAPHY - A HUMAN INVIVO COMPARISON OF VESSEL SIZE AND MORPHOLOGY [J].