HORMESIS - ARE LOW-DOSES OF IONIZING-RADIATION HARMFUL OR BENEFICIAL

被引：31

作者：

VANWYNGAARDEN, KE ^{[1
]}

PAUWELS, EKJ ^{[1
]}

机构：

[1] UNIV LEIDEN HOSP,DEPT DIAGNOST RADIOL & NUCL MED,2300 RC LEIDEN,NETHERLANDS

来源：

EUROPEAN JOURNAL OF NUCLEAR MEDICINE | 1995年 / 22卷 / 05期

关键词：

HORMESIS; IONIZING RADIATION; EPIDEMIOLOGIC STUDIES; EXPERIMENTAL STUDIES;

D O I：

10.1007/BF00839064

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A review is provided of the literature on radiation hormesis, hormesis being any physiological effect that occurs at low doses and which cannot be anticipated by extrapolating from toxic effects noted at high doses. Epidemiological studies suggesting beneficial effects are considered, and experimental evidence for the existence of hormesis is then appraised. In the latter context, there are possible low-dose effects at the molecular level, at the cellular level and on the organism as a whole. It is concluded that while it is difficult to analyse the effects of low-dose radiation with statistical significance, the concept does permit the reconsideration of the validity of currently accepted notions.

引用

页码：481 / 486

页数：6

共 46 条

[1]

Lorenz E., Some biological effects of long continued irradiation, Am J Roentgenol, 63, (1950)

[2]

Sagan L.A., What is hormesis and why haven't we heard about it before?, Health Phys, 52, pp. 521-525, (1987)

[3]

Stebbing A., Hormesis, the stimulation of growth by low levels of inhibitors, Sci Total Environ, 22, (1982)

[4]

Abbat J.D., Hamilton T.R., Weeks J.L., Epidemiological studies in three corporations covering the Canadian nuclear fuel cycle, (1983)

[5]

Kendall G.M., Muirhead C.R., Macgibbon B.H., O'Hagan J.A., Conquest A.J., Goodhill A.A., Butland B.K., Fell T.P., Jackson D.A., Webb M.A., Haylock R.G.E., Thomas J.M., Silk T.J., First analysis of the national registry for radiation workers. Occupational exposure to ionizing radiation and mortality, (1992)

[6]

Luxin W., Et al., Epidemiological investigation of radiological effects in high background radia,1iion areas of Yangjiang, China, Journal of Radiation Research, 31, pp. 119-136, (1990)

[7]

Tietjen G.L., Plutonium and lung cancer, Health Phys, 52, pp. 625-628, (1987)

[8]

Nambi K.S.V., Soman S.D., Environmental radiation and cancer in India, Health Phys, 52, pp. 653-657, (1987)

[9]

Hickey R.J., Bowers E.J., Spence D.E., Zemel B.S., Clelland A.B., Clelland R.C., Low level ionizing radiation and human mortality: multiregional epidemiological studies, Health Phys, 40, pp. 207-219, (1981)

[10]

Kato H., Schull W.J., Awa A., Akiyama M., Otake M., Dose-response analyses among atomic bomb survivors exposed to low level radiation, Health Phys, 52, pp. 645-652, (1987)

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