SYNTHESIS AND MOLECULAR-STRUCTURE OF PIPLARTINE (=PIPERLONGUMINE)

被引：38

作者：

BOLL, PM

HANSEN, J

SIMONSEN, O

THORUP, N

机构：

[1] ODENSE UNIV, DEPT CHEM, DK-5230 ODENSE, DENMARK

[2] TECH UNIV DENMARK, CHEM DEPT B, STRUCT CHEM GRP, DK-2800 LYNGBY, DENMARK

来源：

TETRAHEDRON | 1984年 / 40卷 / 01期

关键词：

D O I：

10.1016/0040-4020(84)85116-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The structure of piplartine (=piperlongumine) was established as (E)-N-3'',4'',5''-trimethoxycinnamoyl-5,6-dihydro-2(1H)-pyridone (13) by synthesis and by an X-ray crystallographic analysis. Model condensation of (E)-3,4,5-trimethoxycinnamoyl chloride and crotonamide gave not the expected cinnamoylcrotonamide, but (E)-N-3'',4'',5''-trimethoxycinnamoyl-3-chlorobutyramide (12).

引用

页码：171 / 175

页数：5

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