PATHOPHYSIOLOGY OF ACUTE-PANCREATITIS - THE ROLE OF PLATELET-ACTIVATING-FACTOR (PAF-ACETHER)

被引：0
|
作者：
AIS, JG [1 ]
NOVO, C [1 ]
GOMEZGARRE, M [1 ]
LOPEZFARRE, A [1 ]
LOPEZNOVOA, JM [1 ]
ROMEO, JM [1 ]
机构：
[1] UNIV AUTONOMA MADRID,FDN JIMENEZ DIAZ,SERV CIRUGIA APARATO DIGEST,MADRID,SPAIN
来源：
REVISTA ESPANOLA DE ENFERMEDADES DIGESTIVAS | 1992年 / 81卷 / 01期
关键词：
ACUTE PANCREATITIS; PLATELET ACTIVATING FACTOR;
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
PAF-acether (Platelet Activating Factor) is a vasoactive substance appearing in plasma under certain pathological circunstances. The aim of our study was to determine plasma, peritoneal exudate and tissular levels of PAF-acether in bilereflux acute necrohemorrhagic pancreatitis (ANP) in the conscious rat 60 minutes after induction. As we have previously demonstrated, ANP causes overwhelming shock in conscious rats. PAF-acether levels increased in plasma and peritoneal exudate of rats with ANP. In contrast, tissular PAF levels were similar to basal values. In conclusion, these data suggest a role of PAF-acether in the hemodynamic impairment that follows induction of pancreatitis.
引用
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页码：25 / 28
页数：4
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