PREPARATION OF CHIRAL 3-UNSUBSTITUTED BETA-LACTAMS FROM 3-HYDROXY BETA-LACTAMS BY USING THE ALKOXYKETENE-IMINE CYCLOADDITION REACTION AS AN APPROACH TO THE AZETIDINONE RING - A FORMAL SYNTHESIS OF THE CARBAPENEM ANTIBIOTIC (+)-PS-5

被引：53

作者：

PALOMO, C

COSSIO, FP

ONTORIA, JM

ODRIOZOLA, JM

机构：

[1] Departamento de Química Orgánica. Facultad, Química. Universidad

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 26期

关键词：

D O I：

10.1016/0040-4039(91)80701-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Formation of chiral 3-hydroxy beta-lactams from the alkoxyketene-imine cycloaddition reaction followed by deoxygenation under Barton's conditions provided a simple route to optically active 3-unsubstituted beta-lactams.

引用

页码：3105 / 3108

页数：4

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