INTRAVASCULAR CATHETER EXCHANGE AND DURATION OF CANDIDEMIA

被引：189
作者：
REX, JH
BENNETT, JE
SUGAR, AM
PAPPAS, PG
SERODY, J
EDWARDS, JE
WASHBURN, RG
机构：
[1] NIAID, CLIN INVEST LAB, BETHESDA, MD 20892 USA
[2] BOSTON UNIV, HOSP MED CTR, BOSTON, MA 02215 USA
[3] UNIV ALABAMA, BIRMINGHAM, AL USA
[4] UNIV N CAROLINA, CHAPEL HILL, NC USA
[5] WAKE FOREST UNIV, BOWMAN GRAY SCH MED, WINSTON SALEM, NC USA
[6] UNIV CALIF LOS ANGELES, HARBOR MED CTR, TORRANCE, CA 90509 USA
来源：
CLINICAL INFECTIOUS DISEASES | 1995年 / 21卷 / 04期
关键词：
D O I：
10.1093/clinids/21.4.994
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
During a comparative trial of amphotericin B vs, fluconazole for treatment of candidemia in nonneutropenic patients, data on the management of intravascular catheters were collected, Complete records were available for 91% of the 206 study patients, For the subset of patients with a catheter in place at the time of their first positive blood culture, removal and replacement of all intravascular catheters without exchange over a guidewire from a preexisting line on or before the first day the study drug was administered were associated with a reduction in the subsequent mean duration (+/- SE) of candidemia, from 5.6 +/- 0.8 days to 2.6 +/- 0.5 days (P < .001).
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页码：994 / 996
页数：3
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