SALMONELLA VIRULENCE - NEW CLUES TO INTRAMACROPHAGE SURVIVAL

被引：72

作者：

GROISMAN, EA

SAIER, MH

机构：

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 01期

关键词：

D O I：

10.1016/0968-0004(90)90128-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Salmonella are capable of survival in macrophages (cells which have evolved specific mechanisms to kill pathogenic bacteria). One mechanism involves the bactericidal peptides called defensins which insert into phospholipid bilayers to generate transmembrane pores. Synthesis of the Salmonella gene products which determine resistance to defensins has been found to be under the control of a transcriptional regulatory protein termed PhoP. © 1990.

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页码：30 / 33

页数：4

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