FREE-RADICAL SCAVENGING ACTIVITY OF TOKI-SHAKUYAKU-SAN (TJ-23)

被引：0
|
作者：
UEDA, Y
KOMATSU, M
HIRAMATSU, M
机构：
[1] YAMAGATA TECHNOPOLIS FDN,INST LIFE SUPPORT TECHNOL,DIV MED SCI,YAMAGATA 990,JAPAN
[2] MIYAZAKI MED COLL,DEPT PSYCHIAT,MIYAZAKI 88916,JAPAN
来源：
NEUROSCIENCES-JAPAN | 1995年 / 21卷
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We evaluated the free radical scavenging activity of Japanese herbal medicine, Toki-Shakuyaku-San (TJ-23; TSUMURA Co. Ltd., Tokyo, Japan), using with electronspin resonance (ESR) spectrometry. TJ-23 scavenged hydroxyl radicals (.OH), superoxide (O2) and 1,1-diphenyl-2-picrylhydrazyl radicals(DPPH) dose-dependently. It also diminished carbon centered radicals (.C) generated by oxygen stress in the rat cortex homogenate and inhibited thiobarbituric acid-reactive substances(TBARS) formation. These data suggest that TJ-23 has an antioxidant effect and would have a prophylactic effect against aging and other neurological diseases associated with free radical.
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页码：P67 / P70
页数：4
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