FREE-RADICAL SCAVENGING ACTIVITY OF TOKI-SHAKUYAKU-SAN (TJ-23)

被引：0
|
作者：
UEDA, Y
KOMATSU, M
HIRAMATSU, M
机构：
[1] YAMAGATA TECHNOPOLIS FDN,INST LIFE SUPPORT TECHNOL,DIV MED SCI,YAMAGATA 990,JAPAN
[2] MIYAZAKI MED COLL,DEPT PSYCHIAT,MIYAZAKI 88916,JAPAN
来源：
NEUROSCIENCES-JAPAN | 1995年 / 21卷
关键词：
D O I：
暂无
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
We evaluated the free radical scavenging activity of Japanese herbal medicine, Toki-Shakuyaku-San (TJ-23; TSUMURA Co. Ltd., Tokyo, Japan), using with electronspin resonance (ESR) spectrometry. TJ-23 scavenged hydroxyl radicals (.OH), superoxide (O2) and 1,1-diphenyl-2-picrylhydrazyl radicals(DPPH) dose-dependently. It also diminished carbon centered radicals (.C) generated by oxygen stress in the rat cortex homogenate and inhibited thiobarbituric acid-reactive substances(TBARS) formation. These data suggest that TJ-23 has an antioxidant effect and would have a prophylactic effect against aging and other neurological diseases associated with free radical.
引用
收藏
页码：P67 / P70
页数：4
相关论文
共 50 条
  • [21] NEURO-ENDOCRINE EFFECT OF TOKI-SHAKUYAKU-SAN ON OVULATION IN RATS
    KOYAMA, T
    HAGINO, N
    COTHRON, AW
    SAITO, M
    AMERICAN JOURNAL OF CHINESE MEDICINE, 1989, 17 (1-2): : 29 - 33
  • [22] EFFECT OF TOKI-SHAKUYAKU-SAN ON OVULATION INDUCED BY HUMAN MENOPAUSAL GONADOTROPIN IN RATS
    KOYAMA, T
    HAGINO, N
    COTHRON, AW
    SAITO, M
    AMERICAN JOURNAL OF CHINESE MEDICINE, 1988, 16 (3-4): : 169 - 172
  • [23] The application of Toki-Shakuyaku-San (TJ-2), a Japanese herbal medicine, on behavioral and psychological symptoms of dementia and psychotic states in the elderly
    Egami, H.
    Shoji, S.
    Inanaga, K.
    Kuniyoshi, M.
    Oyama, S.
    Shingaki, Y.
    Omaru, M.
    Tashiro, S.
    Maeda, H.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2006, 9 : S261 - S261
  • [24] Improved fertility through superoxide removal by Toki-shakuyaku-san in mice - a preliminary study
    Ota, H
    Igarashi, S
    Tanaka, T
    REPRODUCTION FERTILITY AND DEVELOPMENT, 1999, 11 (7-8) : 451 - 455
  • [25] Effects of single and repeated administrations of Toki-shakuyaku-san on the concentrations of brain neurotransmitters in mice
    Itoh, T
    Murai, S
    Saito, H
    Masuda, Y
    METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY, 1998, 20 (01): : 11 - 17
  • [26] Toki-shakuyaku-san, a Japanese kampo medicine, reduces colon inflammation in a mouse model of acute colitis
    Sreedhar, Remya
    Arumugam, Somasundaram
    Thandavarayan, Rajarajan A.
    Giridharan, Vijayasree V.
    Karuppagounder, Vengadeshprabhu
    Pitchaimani, Vigneshwaran
    Afrin, Rejina
    Harima, Meilei
    Nakamura, Takashi
    Ueno, Kazuyuki
    Nakamura, Masahiko
    Suzuki, Kenji
    Watanabe, Kenichi
    INTERNATIONAL IMMUNOPHARMACOLOGY, 2015, 29 (02) : 869 - 875
  • [27] FREE-RADICAL SCAVENGING ACTIVITY OF CARNOSINE
    SALIMHANNA, M
    LISSI, E
    VIDELA, LA
    FREE RADICAL RESEARCH COMMUNICATIONS, 1991, 14 (04): : 263 - 270
  • [28] Effect of traditional Japanese herbal medicine toki-shakuyaku-san for mild cognitive impairment: SPECT study
    Kitabayashi, Yurinosuke
    Shibata, Keisuke
    Nakamae, Takashi
    Narumoto, Jin
    Fukui, Kenji
    PSYCHIATRY AND CLINICAL NEUROSCIENCES, 2007, 61 (04) : 447 - 448
  • [29] Toki-Shakuyaku-San intervenes in apoptosis induced by lowering of potassium chloride concentrations in cultured cerebellar granule cells
    Zhang, XQ
    Hagino, N
    PHYTOTHERAPY RESEARCH, 1998, 12 (04) : 243 - 249
  • [30] THE LEARNING-ABILITY AND MOTILITY OF SENESCENCE ACCELERATED MICE (SAM-P/1) TREATED WITH TOKI-SHAKUYAKU-SAN
    KISHIKAWA, M
    NISHIMURA, M
    SAKAE, M
    ISEKI, M
    PHYTOTHERAPY RESEARCH, 1993, 7 : S63 - S66
12345