FREE-RADICAL SCAVENGING ACTIVITY OF TOKI-SHAKUYAKU-SAN (TJ-23)

被引：0

作者：

UEDA, Y

KOMATSU, M

HIRAMATSU, M

机构：

[1] YAMAGATA TECHNOPOLIS FDN,INST LIFE SUPPORT TECHNOL,DIV MED SCI,YAMAGATA 990,JAPAN

[2] MIYAZAKI MED COLL,DEPT PSYCHIAT,MIYAZAKI 88916,JAPAN

来源：

NEUROSCIENCES-JAPAN | 1995年 / 21卷

关键词：

D O I：

暂无

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We evaluated the free radical scavenging activity of Japanese herbal medicine, Toki-Shakuyaku-San (TJ-23; TSUMURA Co. Ltd., Tokyo, Japan), using with electronspin resonance (ESR) spectrometry. TJ-23 scavenged hydroxyl radicals (.OH), superoxide (O2) and 1,1-diphenyl-2-picrylhydrazyl radicals(DPPH) dose-dependently. It also diminished carbon centered radicals (.C) generated by oxygen stress in the rat cortex homogenate and inhibited thiobarbituric acid-reactive substances(TBARS) formation. These data suggest that TJ-23 has an antioxidant effect and would have a prophylactic effect against aging and other neurological diseases associated with free radical.

引用

页码：P67 / P70

页数：4