HLA ANTIGENS IN ARAB CHILDREN WITH STEROID-RESPONSIVE NEPHROTIC SYNDROME

被引:10
|
作者
ZAKI, M
DAOUD, AS
ALSALEH, QA
ALNAJEDI, AK
WHITE, AG
机构
[1] Department of Paediatrics, Farwania Hospital
[2] Department of Organ Transplantation, Faculty of Medicine, Kuwait University
关键词
HLA; ARABS; NEPHROTIC SYNDROME;
D O I
10.1007/BF00868269
中图分类号
R72 [儿科学];
学科分类号
100202 ;
摘要
Forty-eight Arab patients with steroid-responsive childhood nephrotic syndrome were studied for the frequency of HLA-A, -B, -C and -DR antigens. HLA-DR7 was significantly increased in the patient group (63% vs. 28%, P = 0.0002) confirming reports of a DR7 association in other ethnic groups and indicating a universal association with this antigen. HLA-CW6 was also significantly increased (44% vs. 21%, P corr. = 0.042). HLA-DQW1 was significantly reduced in the patients (29% vs. 57%, P corr. = 0.012) as was HLA-CW4 (6% vs. 24%, P corr. = 0.042).
引用
收藏
页码:74 / 75
页数:2
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