3-BETA-HYDROXY-DELTA-5-STEROID DEHYDROGENASE/3-KETO-DELTA-5-STEROID ISOMERASE FROM BOVINE ADRENALS - MECHANISM OF INHIBITION BY 3-OXO-4-AZA STEROIDS AND KINETIC MECHANISM OF THE DEHYDROGENASE

被引：58

作者：

BRANDT, M ^{[1
]}

LEVY, MA ^{[1
]}

机构：

[1] SK&F LABS,DEPT MED CHEM,DIV RES & DEV,POB 1539,KING OF PRUSSIA,PA 19406

来源：

BIOCHEMISTRY | 1989年 / 28卷 / 01期

关键词：

D O I：

10.1021/bi00427a021

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：140 / 148

页数：9

共 50 条

[1] ACTIVITY OF 3-BETA-HYDROXY-DELTA-5-STEROID DEHYDROGENASE-DELTA-5-DELTA-4-ISOMERASE IN THE OVINE CORPUS-LUTEUM
CAFFREY, JL
NETT, TM
ABEL, JH
NISWENDER, GD
BIOLOGY OF REPRODUCTION, 1979, 20 (02) : 279 - 287
[2] INHIBITION OF 3BETA-HYDROXY-DELTA-5-STEROID DEHYDROGENASE
GOLDMAN, AS
GYNECOLOGIC INVESTIGATION, 1972, 2 (1-6): : 213 - 238
[3] DEGRADATION OF STEROIDS BY INTESTINAL BACTERIA .3. 3-OXO-5BETA STEROID DELTA1 DEHYDROGENASE AND 3-OXO-5BETA STEROID DELTA4 DEHYDROGENASE
ARIES, VC
GODDARD, P
HILL, MJ
BIOCHIMICA ET BIOPHYSICA ACTA, 1971, 248 (03) : 482 - &
[4] A MODIFIED DIGITONIN-PRECIPITATION RADIOASSAY FOR 3-BETA-HYDROXY-DELTA-5-STEROID DEHYDROGENASE
BERKO, EA
THOMAS, JL
STRICKLER, RC
ANALYTICAL BIOCHEMISTRY, 1987, 163 (01) : 36 - 41
[5] INHIBITION OF 3-BETA-HYDROXY-DELTA-5-STEROID DEHYDROGENASE IN RAT TESTICULAR TISSUE BY MERCURIC-CHLORIDE
CHOWDHURY, AR
VACHHRAJANI, KD
CHATTERJEE, BB
TOXICOLOGY LETTERS, 1985, 27 (1-3) : 45 - 49
[6] INTRACELLULAR DISTRIBUTION OF ADRENAL 3BETA-HYDROXY STEROID DEHYDROGENASE AND 3-OXO STEROID DELTA4-DELTA5-ISOMERASE STUDIED WITH ZONAL ROTOR
COWAN, RA
BIDDLECO.W
GILES, CA
GRANT, JK
BIOCHEMICAL JOURNAL, 1972, 126 (03) : P12 - &
[7] INCORPORATION OF BOVINE ADRENAL 3-BETA-HYDROXY-5-ENE STEROID DEHYDROGENASE DELTA(5)-DELTA(4) ISOMERASE INTO PHOSPHOLIPID-VESICLES
YAMAZAKI, T
KOMINAMI, S
NISHIDA, N
TAKEMORI, S
BIOCHIMICA ET BIOPHYSICA ACTA-LIPIDS AND LIPID METABOLISM, 1995, 1257 (03): : 293 - 296
[8] CONTROL OF PLACENTAL 3-BETA-HYDROXY-DELTA-5-STEROID DEHYDROGENASE - APPARENT ENDOGENOUS REGULATOR OF PROGESTERONE SYNTHESIS
WIENER, M
REINER, JM
MECHANISMS OF AGEING AND DEVELOPMENT, 1978, 7 (06) : 445 - 453
[9] 3-OXO-5-ALPHA-STEROID DELTA-4-DEHYDROGENASE AND 3-OXO-5-BETA-STEROID DELTA-4-DEHYDROGENASE IN NORMAL MEN AND IN PATIENTS WITH LIVER-DISEASES
GRAEF, V
GOLF, SW
KRUPP, A
KRATZ, F
JOURNAL OF CLINICAL CHEMISTRY AND CLINICAL BIOCHEMISTRY, 1985, 23 (09): : 583 - 583
[10] TOPOLOGY OF 3-BETA-HYDROXY-5-ENE-STEROID DEHYDROGENASE/DELTA(5)-DELTA(4)-ISOMERASE IN ADRENAL-CORTEX MITOCHONDRIA AND MICROSOMES
SAUER, LA
CHAPMAN, JC
DAUCHY, RT
ENDOCRINOLOGY, 1994, 134 (02) : 751 - 759

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