CLINICAL APPRAISAL OF INSULIN GASTRIC ANALYSIS

Insulin gastric analysis, properly performed and interpreted, is a reliable indicator of postoperative clinical status of patients with peptic ulcer. It can be used to assess the adequacy of vagotomy or antrectomy. Clinical experience with insulin gastric analysis confirms the findings of animal studies which indicate that cephalic secretion is essentially an integrated neurohumoral response, involving a vagal release of antral gastrin. The profound depression of basal acid in the negative-response group also indicates that basal secretion is largely under cephalic control. © 1968 Hoeber Medical Division • Harper & Row.