AVERSIVE TASTE STIMULI INCREASE CGRP LEVELS IN THE GUSTATORY INSULAR CORTEX OF THE RAT

被引：13

作者：

YAMAMOTO, T ^{[1
]}

MATSUO, R ^{[1
]}

ICHIKAWA, H ^{[1
]}

WAKISAKA, S ^{[1
]}

AKAI, M ^{[1
]}

IMAI, Y ^{[1
]}

YONEHARA, N ^{[1
]}

INOKI, R ^{[1
]}

机构：

[1] OSAKA UNIV, FAC DENT, DEPT ORAL ANAT & PHARMACOL, SUITA, OSAKA 565, JAPAN

来源：

NEUROSCIENCE LETTERS | 1990年 / 112卷 / 2-3期

关键词：

Calcitonin gene-related peptide; Immunohistochemistry; Insular cortex; Radioimmunoassay; Taste;

D O I：

10.1016/0304-3940(90)90197-H

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

Calcitonin gene-related peptide-like immunoreactivity (CGRP-IR) was surveyed immunohistochemically in the insular cortex of the rat, and the levels of insular cortical CGRP-IR were measured with the radioimmunoassay method following intraoral stimulation with various taste stimuli. CGRP-IR was localized in nerve fibers within the agranular and dysgranular insular cortices. The CGRP-IR levels in the rostral (gustatory) part of the insular cortex were increased significantly by strongly aversive taste stimuli such as quinine hydrochloride and conditioned taste stimuli (NaCl and sucrose) which animals had been taught to avoid. The results suggest that CGRP in the gustatory insular cortex is concerned with rejection or avoidance behaviors to aversive taste stimuli. © 1990.

引用

页码：167 / 172

页数：6

共 28 条

[1] AVERSIVE TASTE STIMULI FACILITATE EXTRACELLULAR ACETYLCHOLINE-RELEASE IN THE INSULAR GUSTATORY CORTEX OF THE RAT - A MICRODIALYSIS STUDY
SHIMURA, T
SUZUKI, M
YAMAMOTO, T
BRAIN RESEARCH, 1995, 679 (02) : 221 - 226
[2] Spatially Distributed Representation of Taste Quality in the Gustatory Insular Cortex of Behaving Mice
Chen, Ke
Kogan, Joshua F.
Fontanini, Alfredo
CURRENT BIOLOGY, 2021, 31 (02) : 247 - +
[3] Neuronal representations of stimuli in the mouth: The primate insular taste cortex, orbitofrontal cortex and amygdala
Kadohisa, M
Rolls, ET
Verhagen, JV
CHEMICAL SENSES, 2005, 30 (05) : 401 - 419
[4] Inhibitory Gating of Thalamocortical Inputs onto Rat Gustatory Insular Cortex
Haley, Melissa S.
Fontanini, Alfredo
Maffei, Arianna
JOURNAL OF NEUROSCIENCE, 2023, 43 (44) : 7294 - 7306
[5] Bilateral lesions of the insular cortex or of the prefrontal cortex block the association between taste and odor in the rat
Sakai, N
Imada, S
NEUROBIOLOGY OF LEARNING AND MEMORY, 2003, 80 (01) : 24 - 31
[6] Viewing images of foods evokes taste quality-specific activity in gustatory insular cortex
Avery, Jason A.
Liu, Alexander G.
Ingeholm, John E.
Gotts, Stephen J.
Martin, Alex
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2021, 118 (02)
[7] Consolidation of an aversive taste memory requires two rounds of transcriptional and epigenetic regulation in the insular cortex
Alfredo Rodriguez-Blanco, Luis
Rivera-Olvera, Alejandro
Escobar, Martha L.
BEHAVIOURAL BRAIN RESEARCH, 2019, 356 : 371 - 374
[8] DIFFERENTIAL INVOLVEMENT OF GUSTATORY INSULAR CORTEX AND AMYGDALA IN THE ACQUISITION AND RETRIEVAL OF CONDITIONED TASTE-AVERSION IN RATS
GALLO, M
ROLDAN, G
BURES, J
BEHAVIOURAL BRAIN RESEARCH, 1992, 52 (01) : 91 - 97
[9] Extinction of aversive taste memory homeostatically prevents the maintenance of in vivo insular cortex LTP: Calcineurin participation
Rivera-Olvera, Alejandro
Nelson-Mora, Janikua
Gonsebatt, Maria E.
Escobar, Martha L.
NEUROBIOLOGY OF LEARNING AND MEMORY, 2018, 154 : 54 - 61
[10] Effects of insular cortex lesions on conditioned taste aversion and latent inhibition in the rat
Roman, Christopher
Reilly, Steve
EUROPEAN JOURNAL OF NEUROSCIENCE, 2007, 26 (09) : 2627 - 2632

← 1 2 3 →