EFFECT OF TIAPRIDE ON ELECTROACUPUNCTURE ANALGESIA

被引：0
|
作者：
DAI, JL
XU, SF
机构：
来源：
ACTA PHARMACOLOGICA SINICA | 1991年 / 12卷 / 03期
关键词：
TIAPRIDE; BETA-ENDORPHIN; ACUPUNCTURE; ANALGESIA; RADIOIMMUNOASSAY;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Tiapride icv 400-mu-g/rabbit exhibited analgesic and synergistic effects on electroacupuncture analgesia (EAA) in rabbits. Both electroacupuncture (EA) and tiapride (icv 400-mu-g/rabbit) enhanced the beta-endorphin-like immunoreactive substance (beta-EPIS) level in cerebrospinal fluid (CSF) measured by radioimmunoassay (RIA). When EA and tiapride were used in combination, a further increase of beta-EPIS content was found. The results suggested that promotion of beta-EPIS release by tiapride may be one of the mechanisms of synergistic effect of tiapride on EAA.
引用
收藏
页码：212 / 215
页数：4
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