ION CHROMATOGRAPHIC DETERMINATION OF PERCHLORATE IN CATTLE URINE

Much research has been done over the years on the subject of thyreostatic drugs of the thiouracil type in cattle fattening. These substances increase body weight by enlarged filling of the gastro-intestinal tract and by augmented water retention. On the other hand, little work has been done on the elimination and the presence of residues of inorganic thyreostatics such as perchlorate. The aim of this study was to evaluate the elimination of ammonium perchlorate in cattle urine according to the concentration given and the duration of administration. Perchlorate concentrations were measured by mobile phase ion chromatography. The detection limit was 0.1 mg kg-1 for tenfold diluted urine.