THE HEPATITIS-B VIRUS-X PROTEIN TRANSACTIVATION OF C-FOS AND C-MYC PROTOONCOGENES IS MEDIATED BY MULTIPLE TRANSCRIPTION FACTORS

被引:0
|
作者
AVANTAGGIATI, ML
BALSANO, C
NATOLI, G
DEMARZIO, E
WILL, H
ELFASSI, E
LEVRERO, M
机构
[1] POLICLIN UMBERTO 1,FDN ANDREA CESALPINO,MED CLIN 1,GENET EXPRESS LAB,I-00161 ROME,ITALY
[2] MAX PLANCK INST BIOCHEM,W-8033 MARTINSRIED,GERMANY
[3] INST PASTEUR,UNITE IMMUNOL MICROBIENNE,F-75724 PARIS 15,FRANCE
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D O I
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中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
We have constructed two expression vectors in order to study the action of the HBV 17 Kd X protein on the c-fos and c-myc promoters. The results show that the promoters contain multiple elements that respond to X protein, suggesting involvement of multiple transcription factors. The exact mechanism of the interaction remains elusive, but our data allow speculation about the factors that may be influenced.
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页码:57 / 61
页数:5
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