NEW CHIRAL MIXED AMPP LIGANDS AND THEIR USE IN ASYMMETRIC HYDROGENATION OF ACTIVATED KETONES ON RHODIUM CATALYSTS

被引：33

作者：

HATAT, C ^{[1
]}

KOKEL, N ^{[1
]}

MORTREUX, A ^{[1
]}

PETIT, F ^{[1
]}

机构：

[1] UNIV SCI & TECH LILLE,F-59652 VILLENEUVE DASCQ,FRANCE

来源：

TETRAHEDRON LETTERS | 1990年 / 31卷 / 29期

关键词：

D O I：

10.1016/S0040-4039(00)97563-4

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Chiral bidentate aminophosphinephosphinites (AMPP) ligands bearing different substituents at the aminophosphine and the phosphinite moieties are prepared in a one pot synthesis from aminoalcohols. Their use in asymmetric hydrogenation of activated ketones is described. Upon analysis of these results, it is suggested that the phosphinamido group governs both the activity and the enantioselectivity of this reaction. © 1990.

引用

页码：4139 / 4142

页数：4

共 6 条

[1]

BUONO G, 1982, SYNTHESIS-STUTTGART, P1030

[2] ASYMMETRIC REACTIONS CATALYZED BY CHIRAL METAL-COMPLEXES .25. SYNTHESIS AND APPLICATION OF A NOVEL BISPHOSPHINE LIGAND, (-)-DIOCP, AS AN UNSYMMETRIZED DIOP TO PROVE THE GENERAL UTILITY OF NEW DESIGNING CONCEPT [J].