Successful onco-testicular sperm extraction from a testicular cancer patient with a single testis and azoospermia

被引：6

作者：

Kuroda, Shinnosuke ^{[1
]}

Kondo, Takuya ^{[1
]}

Mori, Kohei ^{[1
]}

Yasuda, Kengo ^{[1
]}

Asai, Takuo ^{[1
]}

Sanjo, Hiroyuki ^{[1
]}

Yakanaka, Hiroyuki ^{[1
]}

Takeshima, Teppei ^{[1
]}

Kawahara, Takashi ^{[2
]}

Kato, Yoshitake ^{[1
]}

Miyoshi, Yasuhide ^{[2
]}

Uemura, Hiroji ^{[2
]}

Iwasaki, Akira ^{[1
]}

Yumura, Yasushi ^{[1
]}

机构：

[1] Yokohama City Univ, Med Ctr, Reprod Ctr, Dept Urol, Yokohama, Kanagawa, Japan

[2] Yokohama City Univ, Med Ctr, Dept Urol & Renal Transplantat, Yokohama, Kanagawa, Japan

来源：

CLINICAL AND EXPERIMENTAL REPRODUCTIVE MEDICINE-CERM | 2018年 / 45卷 / 01期

关键词：

Male infertility; Testicular neoplasms; Testicular sperm retrieval;

D O I：

10.5653/cerm.2018.45.1.44

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Onco-testicular sperm extraction is used to preserve fertility in patients with bilateral testicular tumors and azoospermia. We report the case of a testicular tumor in the solitary testis of a patient who had previously undergone successful contralateral orchiectomy and whose sperm was preserved by onco-testicular sperm extraction. A 35-year-old patient presented with swelling of his right scrotum that had lasted for 1 month. His medical history included a contralateral orchiectomy during childhood. Ultrasonography revealed a mosaic echoic area in his scrotum, suggesting a testicular tumor. The lesion was palpated within the normal testicular tissue along its edge and semen analysis showed azoospermia. Radical inguinal orchiectomy and onco-testicular sperm extraction were performed simultaneously. Motile spermatozoa were extracted from normal seminiferous tubules under microscopy and were frozen. Eventual intracytoplasmic sperm injection using the frozen spermatozoa is planned. Onco-testicular sperm extraction is an important fertility preservation method in patients with bilateral testicular tumors or a history of a previous contralateral orchiectomy.

引用

页码：44 / 47

页数：4

共 12 条

[1] Guidelines on Testicular Cancer: 2015 Update [J].

Albers, Peter ;

Albrecht, Walter ;

Algaba, Ferran ;

Bokemeyer, Carsten ;

Cohn-Cedermark, Gabriella ;

Fizazi, Karim ;

Horwich, Alan ;

Laguna, Maria Pilar ;

Nicolai, Nicola ;

Oldenburg, Jan .

EUROPEAN UROLOGY, 2015, 68 (06) :1054-1068

[2] Predictors of Spermatogenesis in Orchiectomy Specimens [J].

Choy, Jeremy T. ;

Wiser, H. Joseph ;

Bell, Stephen W. ;

Cashy, John ;

Brannigan, Robert E. ;

Koehler, Tobias S. .

UROLOGY, 2013, 81 (02) :288-292

[3] Testicular sperm extraction in a single cancerous testicle in patients with azoospermia: a case report [J].

Descombe, Laure ;

Chauleur, Celine ;

Gentil-Perret, Anne ;

Aknin-Seifer, Isabelle ;

Tostain, Jacques ;

Levy, Rachel .

FERTILITY AND STERILITY, 2008, 90 (02) :443.e1-443.e4

[4]

EINHORN LH, 1981, CANCER RES, V41, P3275

[5] Onco-testicular sperm extraction: testicular sperm extraction in azoospermic and very severely oligozoospermic cancer patients [J].

Furuhashi, K. ;

Ishikawa, T. ;

Hashimoto, H. ;

Yamada, S. ;

Ogata, S. ;

Mizusawa, Y. ;

Matsumoto, Y. ;

Okamoto, E. ;

Kokeguchi, S. ;

Shiotani, M. .

ANDROLOGIA, 2013, 45 (02) :107-110

[6] The effect of cancer therapy on fertility, the assessment of fertility and fertility preservation options for pediatric patients [J].

Ginsberg, Jill P. .

EUROPEAN JOURNAL OF PEDIATRICS, 2011, 170 (06) :703-708

[7] Fertility Preservation for Patients With Cancer: American Society of Clinical Oncology Clinical Practice Guideline Update [J].

Loren, Alison W. ;

Mangu, Pamela B. ;

Beck, Lindsay Nohr ;

Brennan, Lawrence ;

Magdalinski, Anthony J. ;

Partridge, Ann H. ;

Quinn, Gwendolyn ;

Wallace, W. Hamish ;

Oktay, Kutluk .

JOURNAL OF CLINICAL ONCOLOGY, 2013, 31 (19) :2500-+

[8] Onco-testicular sperm extraction: birth of a healthy baby after fertility preservation in synchronous bilateral testicular cancer and azoospermia [J].

Roque, M. ;

Sampaio, M. ;

de Oliveira Salles, P. G. ;

Geber, S. .

ANDROLOGIA, 2015, 47 (04) :482-485

[9] Concomitant unilateral and synchronous bilateral testis cancer in azoospermic dizygotic twins: differential management of fertility preservation [J].

Safsaf, Athmane ;

Sibert, Louis ;

Cleret, Jean-Marc ;

Perdrix, Anne ;

Milazzo, Jean-Pierre ;

Gobet, Francoise ;

Mace, Bertrand ;

Rives, Nathalie .

FERTILITY AND STERILITY, 2011, 95 (07) :2434.e11-2434.e13

[10] ONCO-TESE:: Testicular sperm extraction in azoospermic cancer patients before chemotherapy -: New guidelines? [J].

Schrader, M ;

Müller, M ;

Sofikitis, N ;

Straub, B ;

Krause, H ;

Schostak, M ;

Miller, K .

UROLOGY, 2003, 61 (02) :421-425

← 1 2 →