INVESTIGATION OF THE ANTISPASMODIC POTENTIAL OF HIBISCUS-SABDARIFFA CALYXES

被引：42

作者：

ALI, MB ^{[1
]}

SALIH, WM ^{[1
]}

MOHAMED, AH ^{[1
]}

HOMEIDA, AM ^{[1
]}

机构：

[1] UNIV KHARTOUM,DEPT VET MED PHARMACOL & TOXICOL,KHARTOUM,SUDAN

来源：

JOURNAL OF ETHNOPHARMACOLOGY | 1991年 / 31卷 / 02期

关键词：

D O I：

10.1016/0378-8741(91)90009-3

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Addition of an aqueous extract of Hibiscus sabdariffa calyces (2.5 ml/bath almost-equal-to 125 mg of starting crude material) inhibited the tone of various isolated muscle preparations (rabbit aortic strip, rhythmically contracting rat uterus, guinea-pig tracheal chain and rat diaphragm). Other muscles were stimulated (quiescent rat uterus and frog rectus abdominis). Intravenous injection of the extract to anaesthetized cats lowered the blood pressure in a dose-response manner. The inhibitory effects were resistant to a number of standard receptor blockers but the hypotensive influence was partially blocked by atropine and the tonic effects on rat uterus were partially reduced by hydrocortisone and indomethacin.

引用

页码：249 / 257

页数：9

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