A Case of Paraplegia Associated with Intrathecal Methotrexate -A case report-

被引：0

作者：

Lee, Chang Han ^{[1
]}

Oh, Min Kyun

Cho, Jin Hong

Lee, Eun Shin

Shin, Hee Suk

机构：

[1] Gyeongsang Natl Univ, Coll Med, Dept Rehabil Med, Jinju, South Korea

来源：

ANNALS OF REHABILITATION MEDICINE-ARM | 2006年 / 30卷 / 02期

关键词：

Intrathecal methotrexate; Paraplegia; Meningeal leukemia;

D O I：

暂无

中图分类号：

R49 [康复医学];

学科分类号：

100215 ;

摘要：

The treatment and prophylactic therapy of meningeal leukemia with intrathecal methotrexate in acute lymphoblastic leukemia is the standard method. Intrathecal overdose of methotrexate may produce severe toxicities such as paraplegia. We experienced a case of paraplegia diagnosed by magnetic imaging examination of the spine in a 24-year-old woman received repeated intrathecal methotrexate for meningeal leukemia.

引用

页码：188 / 190

页数：3

共 8 条

[1]

BACK EH, 1969, LANCET, V2, P1005

[2] NEUROTOXICITY AND ELEVATED CEREBROSPINAL-FLUID METHOTREXATE CONCENTRATION IN MENINGEAL LEUKEMIA [J].

BLEYER, WA ;

DRAKE, JC ;

CHABNER, BA .

NEW ENGLAND JOURNAL OF MEDICINE, 1973, 289 (15) :770-773

[3]

GEISER CF, 1975, BLOOD, V45, P189

[4]

MCLEAN DR, 1994, CANCER, V73, P3037, DOI 10.1002/1097-0142(19940615)73:12<3037::AID-CNCR2820731223>3.0.CO

[5]

2-6

[6]

SAIKI JH, 1972, CANCER, V29, P370, DOI 10.1002/1097-0142(197202)29:2<370::AID-CNCR2820290217>3.0.CO

[7]

2-Z

[8]

WERNER RA, 1988, ARCH PHYS MED REHAB, V69, P1054

← 1 →