Purpose: To evaluate the results of combined phacoemulsification, insertion of foldable posterior chamber intraocular lens and pars plana vitrectomy for patients with cataract and vitreoretinal disorders. Methods: In this retrospective study, phacoemulsification, IOL (Intraocular lens) implantation, and pars plana vitrectomy were performed in 30 eyes of 29 patients between January 2000-April 2003. Patients ages ranged from 8-82 years (mean 55.9 +/- 19.7) In all cases, phacoemulsification and IOL implantantation were performed through clear corneal inscision before pars plana vitrectomy. Results: Indications of PPV were vitreous hemorrhage (diabetes, retinil branch vein occlusion, trauma), epiretinal membrane, vitreous opacities (posterior uveitis or-asteroides hyalosis), macular hole and rhegmatogenous retinal detachment. Preoperative visual acuity ranged from hand movements (HM) to counting fingers and postoperative visual acuity ranged from HM to 0.7. Postoperatively, visual acuity improved in 23 eyes, was unchanged in 6 eyes, and was worse in 1 eye. Postoperative complications included fibrinoid reaction, posterior sinechia, high intraocular pressure, transient vitreous hemorrhage and recurrent corneal epithelial defect. Conclusions: Phacoemulsification, endocapsular IOL implantation and pars plana vitrectomy is safe and effective technique in selected patients with significant lens opacities and vitreoretinal pathology.