THE HUMAN GENE ENCODING PHOSPHATIDYLINOSITOL-3 KINASE ASSOCIATED P85-ALPHA IS AT CHROMOSOME REGION 5Q12-13

被引:0
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作者
CANNIZZARO, LA
SKOLNIK, EY
MARGOLIS, B
CROCE, CM
SCHLESINGER, J
HUEBNER, K
机构
[1] TEMPLE UNIV, HLTH SCI CTR, SCH MED, FELS INST CANC RES & MOLEC BIOL, PHILADELPHIA, PA 19140 USA
[2] NYU MED CTR, DEPT PHARMACOL, NEW YORK, NY 10016 USA
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
The human chromosomal location of the gene encoding the phosphatidylinositol-3 kinase associated protein, p85-alpha, has been determined by analysis of its segregation in rodent-human hybrids and by chromosome in situ hybridization using a complementary DNA clone, GRB-1. The gene for p85-alpha is at chromosome region 5ql3, perhaps near the gene encoding another receptor associated signal transducing protein, the GTPase activating protein.
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页码:3818 / 3820
页数:3
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