TREATMENT OF INFANTS WITH NEUROGENIC BLADDER DYSFUNCTION USING ANTICHOLINERGIC DRUGS AND INTERMITTENT CATHETERIZATION

被引：37

作者：

BASKIN, LS ^{[1
]}

KOGAN, BA ^{[1
]}

BENARD, F ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,DEPT UROL,U-518,SAN FRANCISCO,CA 94143

来源：

BRITISH JOURNAL OF UROLOGY | 1990年 / 66卷 / 05期

关键词：

D O I：

10.1111/j.1464-410X.1990.tb15004.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Summary— The use of anticholinergic drugs in infants with neurogenic dysfunction has not been well documented. In this study, 35 neonates at risk of upper urinary tract damage from neurogenic dysfunction were treated from infancy with anticholinergics, in combination with clean intermittent catheterisation. None of the patients showed upper urinary tract deterioration with follow‐up ranging from 6 to 72 months, although 2 required vesicostomy–1 due to difficulty with catheterisation and 1 due to possible anticholinergic side effects. Only 2 (6%) have had clinical pyelonephritis. Twenty‐five (76%) are virtually dry between catheterisation. We conclude that anticholinergics are safe and effective, even in the neonatal period, when used in combination with clean intermittent catheterisation for the treatment of neonates with neurogenic bladder dysfunction. © 1990 British Journal of Urology

引用

页码：532 / 534

页数：3

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