INHIBITION BY MEPACRINE AND PARA-BROMOPHENACYLBROMIDE OF PHOSPHOINOSITIDE HYDROLYSIS, GLUCOSE-OXIDATION, CALCIUM-UPTAKE AND INSULIN RELEASE IN RAT PANCREATIC-ISLETS

被引：53
作者：
BEST, L [1 ]
SENER, A [1 ]
MATHIAS, PCF [1 ]
MALAISSE, WJ [1 ]
机构：
[1] FREE UNIV BRUSSELS,EXPTL MED LAB,B-1000 BRUSSELS,BELGIUM
来源：
BIOCHEMICAL PHARMACOLOGY | 1984年 / 33卷 / 16期
关键词：
D O I：
10.1016/0006-2952(84)90641-5
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：2657 / 2662
页数：6
相关论文
共 27 条
[1]   LITHIUM AMPLIFIES AGONIST-DEPENDENT PHOSPHATIDYLINOSITOL RESPONSES IN BRAIN AND SALIVARY-GLANDS [J].
BERRIDGE, MJ ;
DOWNES, CP ;
HANLEY, MR .
BIOCHEMICAL JOURNAL, 1982, 206 (03) :587-595
[2]   EFFECTS OF NUTRIENT SECRETAGOGUES UPON PHOSPHOLIPID-METABOLISM IN RAT PANCREATIC-ISLETS [J].
BEST, L ;
MALAISSE, WJ .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1983, 32 (2-3) :205-214
[3]   STIMULATION OF PHOSPHOINOSITIDE BREAKDOWN IN RAT PANCREATIC-ISLETS BY GLUCOSE AND CARBAMYLCHOLINE [J].
BEST, L ;
MALAISSE, WJ .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1983, 116 (01) :9-16
[4]   REGULATION OF RB-86(+) OUTFLOW FROM PANCREATIC-ISLETS .1. RECIPROCAL CHANGES IN THE RESPONSE TO GLUCOSE, TETRAETHYLAMMONIUM AND QUININE [J].
CARPINELLI, A ;
MALAISSE, WJ .
MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1980, 17 (02) :103-110
[5]   STIMULUS-SECRETION COUPLING OF GLUCOSE-INDUCED INSULIN RELEASE - EFFECT OF INTRACELLULAR ACIDIFICATION UPON CALCIUM EFFLUX FROM ISLET CELLS [J].
CARPINELLI, AR ;
SENER, A ;
HERCHUELZ, A ;
MALAISSE, WJ .
METABOLISM-CLINICAL AND EXPERIMENTAL, 1980, 29 (06) :540-545
[6]  
DISE CA, 1982, J BIOL CHEM, V257, P4701
[7]   IMPORTANCE OF PHOSPHOLIPASE-A2 IN PROSTAGLANDIN BIOSYNTHESIS [J].
FLOWER, RJ ;
BLACKWELL, GJ .
BIOCHEMICAL PHARMACOLOGY, 1976, 25 (03) :285-291
[8]  
FRYE RA, 1983, MOL PHARMACOL, V23, P547
[9]   REGULATION OF CALCIUM FLUXES IN RAT PANCREATIC-ISLETS - CALCIUM EXTRUSION BY SODIUM-CALCIUM COUNTERTRANSPORT .4. [J].
HERCHUELZ, A ;
SENER, A ;
MALAISSE, WJ .
JOURNAL OF MEMBRANE BIOLOGY, 1980, 57 (01) :1-12
[10]   REGULATION OF CALCIUM FLUXES IN RAT PANCREATIC-ISLETS .9. QUININE MIMICS THE DUAL EFFECT OF GLUCOSE ON CALCIUM MOVEMENTS [J].
HERCHUELZ, A ;
LEBRUN, P ;
CARPINELLI, A ;
THONNART, N ;
SENER, A ;
MALAISSE, WJ .
BIOCHIMICA ET BIOPHYSICA ACTA, 1981, 640 (01) :16-30
123