Two-Stage Revision TKA Is Associated with High Complication and Failure Rates

被引:39
作者
Pelt, Christopher E. [1 ]
Grijalva, Ray [1 ]
Anderson, Lucas [1 ]
Anderson, Mike B. [1 ]
Erickson, Jill [1 ]
Peters, Christopher L. [1 ]
机构
[1] Univ Utah, Dept Orthopaed Surg, 590 Wakara Way, Salt Lake City, UT 84108 USA
关键词
D O I
10.1155/2014/659047
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
Despite two-stage revision remaining the gold standard in treating periprosthetic infection of total knee arthroplasty (TKA), there remains uncertainty regarding the actual success rate and the risk factors for failure. We retrospectively reviewed 58 knees with mean follow-up of 38 months who underwent two-stage revision TKAs from 1998 to 2012 by a single surgeon. Failure was defined as persistent infection or reoperation after two-stage revision TKA surgery. Failure occurred in 36%. The overall mortality was 22%. The mean time to reinfection was 26 months. Polymicrobial infection was associated with a higher risk of failure (RR 3.31,P < 0.001). Knees requiring soft tissue coverage were also at a greater risk of failure (RR 2.67,P = 0.001), as were knees that underwent four or more additional surgeries after the primary TKA and prior to stage-one explantation (RR 2.25,P = 0.020). Thus, opportunities exist for improvement in management of infected TKA.
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页数:7
相关论文
共 31 条
[1]   Infection after total knee arthroplasty [J].
Blom, AW ;
Brown, J ;
Taylor, AH ;
Pattison, G ;
Whitehouse, S ;
Bannister, GC .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 2004, 86B (05) :688-691
[2]  
Borden L S, 1987, J Arthroplasty, V2, P27, DOI 10.1016/S0883-5403(87)80028-1
[3]  
Cai Pengde, 2012, Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi, V26, P1169
[4]  
Cohen J C, 1988, J Arthroplasty, V3, P369, DOI 10.1016/S0883-5403(88)80040-8
[5]  
Fehring TK, 2000, CLIN ORTHOP RELAT R, P9
[6]  
Gacon G, 1997, REV CHIR ORTHOP, V83, P313
[7]   Can This Prosthesis Be Saved?: Implant Salvage Attempts in Infected Primary TKA [J].
Gardner, Jeremy ;
Gioe, Terence J. ;
Tatman, Penny .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2011, 469 (04) :970-976
[8]   Durable Infection Control and Function With the PROSTALAC Spacer in Two-stage Revision for Infected Knee Arthroplasty [J].
Gooding, Christopher R. ;
Masri, Bassam A. ;
Duncan, Clive P. ;
Greidanus, Nelson V. ;
Garbuz, Donald S. .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2011, 469 (04) :985-993
[9]  
HOFMANN AA, 1995, CLIN ORTHOP RELAT R, P45
[10]   Treatment of infected total knee arthroplasty using an articulating spacer [J].
Hofmann, AA ;
Goldberg, T ;
Tanner, AM ;
Kurtin, SM .
CLINICAL ORTHOPAEDICS AND RELATED RESEARCH, 2005, (430) :125-131