A systematic review of the literature exploring the interplay between prostate cancer and type two diabetes mellitus

被引：23

作者：

Crawley, Danielle ^{[1
]}

Chamberlain, Florence ^{[2
]}

Garmo, Hans ^{[1
]}

Rudman, Sarah ^{[2
]}

Zethelius, Bjorn ^{[3
,4
]}

Holmberg, Lars ^{[1
,5
]}

Adolfsson, Jan ^{[6
]}

Stattin, Par ^{[5
]}

Carroll, Paul ^{[7
]}

Van Hemelrijck, Mieke ^{[1
]}

机构：

[1] Kings Coll London, Translat Oncol & Urol Res Grp, London SE1 9RT, England

[2] Guys & St Thomas NHS Fdn Trust, Dept Med Oncol, London SE1 9RT, England

[3] Uppsala Univ, Dept Publ Hlth & Geriatr, S-75105 Uppsala, Sweden

[4] Med Prod Agcy, S-75103 Uppsala, Sweden

[5] Uppsala Univ, Dept Surg Sci, S-75105 Uppsala, Sweden

[6] Karolinska Inst, Dept Clin Sci Intervent & Technol, S-17177 Stockholm, Sweden

[7] Guys & St Thomas NHS Fdn Trust, Dept Diabet & Endocrinol, London SE1 9RT, England

来源：

ECANCERMEDICALSCIENCE | 2018年 / 12卷

关键词：

type two diabetes; prostate cancer; review;

D O I：

10.3332/ecancer.2018.802

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Prostate cancer (PCa) and type two diabetes mellitus (T2DM) are both increasing prevalent conditions and often occur concurrently. However, the relationship between the two is more complex than just two prevalent conditions co-existing. This review systematically explores the literature around the interplay between the two conditions. It covers the impact of pre-existing T2DM on PCa incidence, grade and stage, as well as exploring the impact of T2DM on PCa outcomes and mortality and the interaction between T2DM and PCa treatments.

引用

页数：27

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