LIPID DOMAINS IN MODEL AND BIOLOGICAL-MEMBRANES

被引：182

作者：

WELTI, R

GLASER, M

机构：

[1] UNIV ILLINOIS,DEPT BIOCHEM,ROGER ADAMS LAB,URBANA,IL 61801

[2] KANSAS STATE UNIV AGR & APPL SCI,DIV BIOL,MANHATTAN,KS 66506

来源：

CHEMISTRY AND PHYSICS OF LIPIDS | 1994年 / 73卷 / 1-2期

基金：

美国国家科学基金会;

关键词：

MEMBRANE STRUCTURE; LATERAL PHASE SEPARATION; IMMISCIBLE MIXTURES; LIPID-PROTEIN INTERACTIONS; CYTOSKELETON; MEMBRANE FUNCTION;

D O I：

10.1016/0009-3084(94)90178-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lipid domains that occur within biological or model membranes encompass a variety of structures with very different lifetimes. The separation of membrane lipids into compositional domains can be due to lateral phase separation, immiscibility within a single phase, or interaction of lipids with integral or peripheral proteins. Lipid domains can affect the extent and rate of reactions in the membrane and provide sites for the activity of specialized proteins. Domains are likely to be involved in the process of lipid sorting to various cellular membranes, as well as in other processes which involve membrane budding or invagination.

引用

页码：121 / 137

页数：17

共 184 条

[1] EVIDENCE FOR PHASE-SEPARATION IN THE MEMBRANE OF AN OSMOTICALLY STABILIZED FATTY-ACID AUXOTROPH OF ESCHERICHIA-COLI AND ITS BIOLOGICAL SIGNIFICANCE [J].