EFFECTS OF MOSSBAUER RADIATION ON BONE-MARROW CULTURES

被引：5

作者：

ORTALLI, I

PEDRAZZI, G

JIANG, K

ZHANG, X

CARLOSTELLA, C

MANGONI, L

RIZZOLI, V

机构：

[1] UNIV PARMA,INST PHYS SCI,VIA DAZEGLIO 85,I-43100 PARMA,ITALY

[2] UNIV PARMA,HEMATOL UNIT,I-43100 PARMA,ITALY

来源：

HYPERFINE INTERACTIONS | 1992年 / 71卷 / 1-4期

关键词：

D O I：

10.1007/BF02397314

中图分类号：

O64 [物理化学（理论化学）、化学物理学]; O56 [分子物理学、原子物理学];

学科分类号：

070203 ; 070304 ; 081704 ; 1406 ;

摘要：

A low radiation dose approach to cell eradication would be highly desirable in cancer treatments in order to reduce the side effects of conventional radiotherapy. In the present work we present a preliminary study on cultures of bone marrow mononuclear cells collected from normal subjects and patients with chronic myelogenous leukaemia (CML). Hematin (10(-4),10(-5),10(-6) M) has been added to marrow culture cells which were then irradiated with a 3.7 GBq (100 mCi) Co-57/Rh Mossbauer source for 4 hours. Significant inhibition has been observed on the cell growth due to hematin and irradiation.

引用

页码：1267 / 1270

页数：4

共 7 条

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