A RAPID, SIMULTANEOUS DETERMINATION OF PARAQUAT AND DIQUAT IN SERUM AND URINE USING 2ND-DERIVATIVE SPECTROSCOPY

被引：36

作者：

FUKE, C

AMENO, K

AMENO, S

KIRIU, T

SHINOHARA, T

SOGO, K

IJIRI, I

机构：

[1] Department of Forensic Medicine, Kagawa Medical School, Kita, Kagawa, 761-07, 1750-1 Ikenobe, Miki

来源：

JOURNAL OF ANALYTICAL TOXICOLOGY | 1992年 / 16卷 / 04期

关键词：

D O I：

10.1093/jat/16.4.214

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A rapid, simple method based on second-derivative spectroscopy of the simultaneous analysis of paraquat and diquat in serum and urine is described. Paraquat and diquat in serum were deproteinized with sulfosalicyllc acid, and those In urine were reduced with NaOH-dithlonite solution. A qualitative and quantitative analysis of reduced paraquat and diquat was made at the amplitude peaks of 396-403 nm and 454-464 nm In the second-derivative spectra, respectively. The entire procedure was completed within about 10 minutes for a serum sample and within about 5 minutes for a urine sample. Application of the proposed method on a poisoned patient is also reported. © 1992, Oxford University Press. All rights reserved.

引用

页码：214 / 216

页数：3

共 7 条

[1]

FUKE C, 1987, PHARMACEUTICALS MONT, V29, P1294

[2] HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY OF PARAQUAT AND DIQUAT IN URINE WITH RAPID SAMPLE PREPARATION INVOLVING ION-PAIR EXTRACTION ON DISPOSABLE CARTRIDGES OF OCTADECYL-SILICA [J].