CONFORMATIONALLY RESTRICTED P1-P1' TRANSITION-STATE ANALOGS - SYNTHESIS OF 1(R), 3(R) [1(S), 2(S)] AND 1(S), 3(S) [1(S), 2(S)] 3-[3-CYCLOHEXYL-2-[(BOC)AMINO]-1-HYDROXYPROPYL]-2,2-DIMETHYLCYCLOPROPANE CARBOXYLIC-ACIDS

被引:20
作者
MELNICK, MJ [1 ]
BISAHA, SN [1 ]
GAMMILL, RB [1 ]
机构
[1] UPJOHN CO,RES LABS,KALAMAZOO,MI 49001
关键词
D O I
10.1016/S0040-4039(00)94403-4
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
A concise synthesis and determination of absolute stereochemistry of two novel diastereomeric cyclopropyl containing transition state mimics is described. © 1990.
引用
收藏
页码:961 / 964
页数:4
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