The evaluation of the fibromyalgia patients

被引:8
作者
Atzeni, F. [1 ]
Salaffi, F. [2 ]
Bazzichi, L. [3 ]
Gracely, R. H. [4 ]
Carignola, R. [5 ]
Torta, R. [5 ]
Gorla, R. [6 ,7 ]
Marsico, A. [8 ]
Ceccherelli, F. [9 ]
Cazzola, M. [10 ]
Buskila, D. [11 ,12 ]
Spath, M. [13 ]
Di Franco, M. [14 ]
Biasi, G. [15 ]
Cassisi, G. [16 ]
Stisi, S. [17 ]
Casale, R. [18 ,19 ]
Altomonte, L. [20 ]
Arioli, G. [21 ]
Alciati, A. [22 ]
Leardini, G. [23 ]
Marinangeli, F. [24 ]
Giamberardino, M. A. [25 ]
Sarzi-Puttini, P. [1 ]
机构
[1] L Sacco Univ Hosp, Rheumatol Unit, Milan, Italy
[2] Polytech Univ Marche Reg, Dept Rheumatol, Ancona, Italy
[3] Univ Pisa, S Chiara Hosp, Dept Internal Med, Div Rheumatol, Pisa, Italy
[4] Univ Michigan Hlth Syst, Dept Med, Ann Arbor, MI USA
[5] Univ Turin, S San Giovanni Battista Turin, Dept Neurosci, Turin, Italy
[6] Spedali Civil Brescia, Rheumatol & Clin Immunol, Brescia, Italy
[7] Univ Brescia, Brescia, Italy
[8] Hosp Taranto, Rheumatol Unit, Taranto, Italy
[9] Univ Padua, IRCCS, IOV Veneto Canc Inst, Dept Pharmacol & Anesthesiol, Padua, Italy
[10] Hosp Circolo, Unit Rehabil Med, Saronno, VA, Italy
[11] Ben Gurion Univ Negev, Soroka Med Ctr, Dept Med H, Beer Sheva, Israel
[12] Ben Gurion Univ Negev, Fac Hlth Sci, Beer Sheva, Israel
[13] Univ Munich, Friedrich Baur Inst, Munich, Germany
[14] Univ Roma La Sapienza, Chair Rheumatol, Rome, Italy
[15] Univ Siena, Unit Rheumatol, Siena, Italy
[16] Specialist Outpatients Dept, Rheumatol Branch, Belluno, Italy
[17] G Rummo Hosp, Rheumatol Unit, Benevento, Italy
[18] Fdn Salvatore Maugeri, IRCCS, Sci Inst Montescano, Dept Clin Neurophysiol, Montescano, PV, Italy
[19] Fdn Salvatore Maugeri, IRCCS, Sci Inst Montescano, Pain Rehabil Unit, Montescano, PV, Italy
[20] UOC Rheumatol Hosp S Eugenio, Rome, Italy
[21] Gen Hosp Pieve Coriano Mantua, Div Rehabil Med & Rheumatol, Mantua, Italy
[22] L Sacco Univ Hosp, Dept Psychiat, Milan, Italy
[23] SS Giovanni & Paolo Hosp, Rheumatol Unit, Venice, Italy
[24] LAquila Univ, Dept Anesthesiol & Pain Med, Laquila, Italy
[25] Univ G dAnnunzio, CeSI G DAnnunzio Fdn, Dept Med & Sci Aging, Chieti, Italy
关键词
Biomarkers; functional magnetic resonance; clinimetric approaches; polysomnography; tilting test;
D O I
10.4081/reumatismo.2008.1s.36
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Fibromyalgia (FM) is a rheumatic disease characterized by musculoskeletal pain, chronic diffuse tension and/or stiffness in joints and muscles, easy fatigue, sleep and emotional disturbances, and pressure pain sensitivity in at least 11 of 18 tender points. At present, there are no instrumental tests or specific diagnostic markers for FM; in fact, many of the existing indicators are significant for research purposes only. Many differential diagnoses may be excluded by an extensive clinical examination and patient history. Considering overlap of FM with other medical conditions, the treating physicians should be vigilant: chest-X-rays and abdominal ultrasonography are the first steps of general evaluation for all the patients with suspected FM. Functional neuroimaging methods have revealed a large number of supraspinal effects in FM, a disorder mediated by mechanisms that are essentially unknown. Many treatments are used in FM patients, but evaluating their therapeutic effects in FM is difficult because the syndrome is so multifaceted. To address the identification of core outcome domains, the Initiative on IMMPACT and OMERACT workshop convened a meeting to develop consensus recommendations for chronic pain clinical trials.
引用
收藏
页码:36 / 49
页数:14
相关论文
共 98 条
[1]   Fibromyalgia frequency in hepatitis B carriers [J].
Adak, B ;
Tekeoglu, I ;
Ediz, L ;
Budancamanak, M ;
Yazgan, T ;
Karahocagil, K ;
Demirel, A .
JCR-JOURNAL OF CLINICAL RHEUMATOLOGY, 2005, 11 (03) :157-159
[2]   Bone health in patients with fibromyalgia [J].
Al-Allaf, AW ;
Mole, PA ;
Paterson, CR ;
Pullar, T .
RHEUMATOLOGY, 2003, 42 (10) :1202-1206
[3]   Free radicals and antioxidants in primary fibromyalgia: an oxidative stress disorder? [J].
Bagis, S ;
Tamer, L ;
Sahin, G ;
Bilgin, R ;
Guler, H ;
Ercan, B ;
Erdogan, C .
RHEUMATOLOGY INTERNATIONAL, 2005, 25 (03) :188-190
[4]   A chronic fatigue syndrome - related proteome in human cerebrospinal fluid [J].
Baraniuk, JN ;
Casado, B ;
Maibach, H ;
Clauw, DJ ;
Pannell, LK ;
Hess, S .
BMC NEUROLOGY, 2005, 5 (1)
[5]  
Bazzichi L, 2007, CLIN EXP RHEUMATOL, V25, P225
[6]   Peripheral benzodiazepine receptors on platelets of fibromyalgic patients [J].
Bazzichi, L. ;
Giannaccini, G. ;
Betti, L. ;
Italiani, P. ;
Fabbrini, L. ;
Defeo, F. ;
Giacomelli, C. ;
Giuliano, T. ;
Rossi, A. ;
Uccelli, A. ;
Giusti, L. ;
Mascia, G. ;
Lucacchini, A. ;
Bombardieri, S. .
CLINICAL BIOCHEMISTRY, 2006, 39 (09) :867-872
[7]  
Bazzichi L, 2007, CLIN RHEUMATOL, P9
[8]   Alteration of serotonin transporter density and activity in fibromyalgia [J].
Bazzichi, Laura ;
Giannaccini, Gino ;
Betti, Laura ;
Mascia, Giovanni ;
Fabbrini, Laura ;
Italiani, Paola ;
De Feo, Francesca ;
Giuliano, Tiziana ;
Giacomelli, Camillo ;
Rossi, Alessandra ;
Lucacchini, Antonio ;
Bombardieri, Stefano .
ARTHRITIS RESEARCH & THERAPY, 2006, 8 (04)
[9]  
BELZA BL, 1993, NURS RES, V42, P93
[10]  
BONAFEDE RP, 1995, J RHEUMATOL, V22, P133