THE IMMUNE STATUS AND ITS CORRECTION IN AMEBIC-ABSCESS OF THE LIVER

The author analyses the results of study of the immune status in 100 patients with amebic abscess of the liver, who were divided into 2 groups. In an uncomplicated course of the disease (50 patients, Group 1) there were no essential shifts in the immune status in the preoperative period. In the postoperative period (1st-3rd day), however, the percentage and absolute number of T-and B-lymphocytes reduced. Due to this, immuno-stimulation therapy (decaris, gamma-globulin, hyper-immune antistaphylococcic plasma, activin) had to be applied. In a complicated course of amebic abscess of the liver (50 patients, group 2) the water-electrolyte metabolism was disturbed and the blood erythrocyte-globular volume was reduced and the cellular and humoral links of immunity were markedly depressed in the preoperative period. Intensive transfusion-infusion therapy had to be conducted along with immunostimulation treatment (decaris, T-activin, gamma-globulin, hyper-immune antistaphylococcic plasma, direct transfusion of blood) and prescription of anabolic hormones (pentoxyl, retabolil).