Influenza virus vaccination and kidney graft rejection: causality or coincidence

被引:15
作者
Fischer, Anne Sophie Lind [1 ]
Moller, Bjarne Kuno [2 ]
Krag, Soren [3 ]
Jespersen, Bente [1 ]
机构
[1] Aarhus Univ Hosp, Dept Nephrol, DK-8200 Skejby N, Arhus, Denmark
[2] Aarhus Univ Hosp, Dept Clin Immunol, DK-8200 Aarhus N, Denmark
[3] Aarhus Univ Hosp, Dept Pathol, DK-8200 Aarhus N, Denmark
来源
CLINICAL KIDNEY JOURNAL | 2015年 / 8卷 / 03期
关键词
acute kidney injury; influenza vaccination; kidney graft rejection; renal transplant recipient;
D O I
10.1093/ckj/sfv027
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Influenza can cause significant morbidity and mortality in renal transplant recipients especially with a high rate of lower respiratory disease. Annual influenza vaccination is therefore recommended to renal transplant recipients. We report the first three cases of acute kidney injury in renal transplant recipients following influenza vaccination that all led to graft loss. They all had different native diseases and were all vaccinated in the same season of 2009-10. The time span from vaccination to decline of kidney function is shorter than the time to diagnosis since the three patients only had blood tests every 3 months or when symptoms became severe. These reports do not justify a change of current recommendations regarding influenza vaccination in renal transplant recipients, but they support the continued attention and registration of vaccinations to monitor side effects.
引用
收藏
页码:325 / 328
页数:4
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