Epigenetic interplay of histone modifications and DNA methylation mediated by HDA6

被引：31
作者：
Liu, Xuncheng [1 ]
Luo, Ming [1 ,2 ]
Wu, Keqiang [1 ]
机构：
[1] Natl Taiwan Univ, Inst Plant Biol, Taipei, Taiwan
[2] Chinese Acad Sci, Key Lab Plant Resources Conservat & Sustainable U, South China Bot Garden, Guangzhou, Guangdong, Peoples R China
来源：
PLANT SIGNALING & BEHAVIOR | 2012年 / 7卷 / 06期
关键词：
HDA6; MET1; FLD; histone deacetylation; DNA methylation; histone demethylation;
D O I：
10.4161/psb.19994
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
One of the most fundamental questions in the control of gene expression is how epigenetic patterns of DNA methylation and histone modifications are established. Our recent studies demonstrate that histone deacetylase HDA6 integrates DNA methylation and histone modifications in gene silencing by interacting with DNA methyltransferase MET1 and histone demethylase FLD, suggesting that regulatory crosstalk between histone modifications and DNA methylation could be mediated by the interaction of various epigenetic modification proteins.
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收藏
页码：633 / 635
页数：3
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