AGING DOES NOT ALTER MUSCARINIC RECEPTOR-MEDIATED INHIBITION OF CYCLIC-AMP FORMATION IN THE STRIATUM AND HIPPOCAMPUS

被引:10
作者
ABDALLAH, EAM [1 ]
POU, WS [1 ]
ELFAKAHANY, EE [1 ]
机构
[1] UNIV MARYLAND,SCH PHARM,DEPT PHARMACOL & TOXICOL,20 N PINE ST,BALTIMORE,MD 21201
关键词
Aging; Cyclic adenosine monophosphate; Fischer; 344; rat; Hippocampus; Muscarinic; Striatum;
D O I
10.1016/0006-8993(90)90133-V
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
The effects of aging on the inhibition of forskolin-stimulated cyclic AMP formation by muscarinic receptors were investigated. There were no detectable changes in the magnitude of maximal inhibition by carbamylcholine or the potency of the agonist in inducing this response in either the striatum or hippocampus obtained from young or old Fisher 344 rats. © 1990.
引用
收藏
页码:234 / 236
页数:3
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