NUCLEOSIDES .132. SYNTHESIS OF 5-(2'-SUBSTITUTED-2'-DEOXY-BETA-D-ARABINOFURANOSYL)-1-METHYLURACILS FROM 1-METHYL-PSI-URIDINE - THE 1ST DIRECT INTRODUCTION OF THE 2'-SUBSTITUENT TO C-2' IN THE UP CONFIGURATION BY NUCLEOPHILIC REACTIONS - STUDIES DIRECTED TOWARD THE SYNTHESIS OF 2'-DEOXY 2'-SUBSTITUTED ARABINO NUCLEOSIDES-3O

被引：17

作者：

PANKIEWICZ, KW ^{[1
]}

KIM, JH ^{[1
]}

WATANABE, KA ^{[1
]}

机构：

[1] CORNELL UNIV,GRAD SCH MED SCI,MEM SLOAN KETTERING CANC CTR,SLOAN KETTERING INST CANC RES,NEW YORK,NY 10021

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1985年 / 50卷 / 18期

关键词：

D O I：

10.1021/jo00218a014

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3319 / 3322

页数：4

共 23 条

[1] SYNTHESIS OF 5-SUBSTITUTED PYRIMIDINES [J].

ASBUN, W ;

BINKLEY, SB .

JOURNAL OF ORGANIC CHEMISTRY, 1966, 31 (07) :2215-&

[2] REACTIONS OF RELEVANCE TO CHEMISTRY OF AMINOGLYCOSIDE ANTIBIOTICS .7. CONVERSION OF THIOCARBONATES INTO DEOXY-SUGARS [J].

BARTON, DHR ;

SUBRAMANIAN, R .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1977, (15) :1718-1723

[3] SYNTHESIS OF DEOXYSUGARS AND OF DEOXYNUCLEOSIDES FROM DIOL THIOCARBONATES [J].

BARTON, DHR ;

SUBRAMANIAN, R .

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1976, (21) :867-868

[4] NOVEL ARABINOFURANOSYL DERIVATIVES OF CYTOSINE RESISTANT TO ENZYMATIC DEAMINATION AND POSSESSING POTENT ANTI-TUMOR ACTIVITY [J].

BOBEK, M ;

CHENG, YC ;

BLOCH, A .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (07) :597-598

[5] NUCLEOTIDES .40. O-2-5'-CYCLOURIDINE AND A SYNTHESIS OF ISOCYTIDINE [J].

BROWN, DM ;

TODD, AR ;

VARADARAJAN, S .

JOURNAL OF THE CHEMICAL SOCIETY, 1957, (FEB) :868-872

[6] NUCLEOSIDES .107. SYNTHESIS OF 5-(BETA-D-ARABINOFURANOSYL)ISOCYTOSINE AND RELATED C-NUCLEOSIDES [J].

CHU, CK ;

REICHMAN, U ;

WATANABE, KA ;

FOX, JJ .

JOURNAL OF MEDICINAL CHEMISTRY, 1978, 21 (01) :96-100

[7]

Fox J J, 1969, Pure Appl Chem, V18, P223, DOI 10.1351/pac196918010223

[8] USE OF P-NITROPHENYL CHLOROFORMATE IN BLOCKING HYDROXYL GROUPS IN NUCLEOSIDES [J].

LETSINGER, RL ;

OGILVIE, KK .

JOURNAL OF ORGANIC CHEMISTRY, 1967, 32 (02) :296-+

[9] NUCLEOSIDES .120. SYNTHESES OF 2' DEOXY-PSI-ISOCYTIDINE AND 2'-DEOXY-1-METHYL-PSI-URIDINE FROM PSI-URIDINE [J].

MATSUDA, A ;

CHU, CK ;

REICHMAN, U ;

PANKIEWICZ, K ;

WATANABE, KA ;

FOX, JJ .

JOURNAL OF ORGANIC CHEMISTRY, 1981, 46 (18) :3603-3609

[10] NUCLEOSIDES .121. IMPROVED AND GENERAL-SYNTHESIS OF 2'-DEOXY C-NUCLEOSIDES - SYNTHESIS OF 5-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)URACIL, 5-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)1-METHYLURACIL, 5-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)1,3-DIMETHYLURACIL, AND 5-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)ISOCYTOSINE [J].

PANKIEWICZ, K ;

MATSUDA, A ;

WATANABE, KA .

JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (03) :485-488

← 1 2 3 →